Exapro is your premier marketplace for high-quality used industrial machinery. We present our selection of granulators under the Pharmaceutical and Chemical category. These machines are professionally maintained, offering an excellent blend of efficiency, durability, and value.

Our granulators excel in processing materials into granules, making them ideal for various applications in the pharmaceutical and chemical industries. Whether you are producing tablets, capsules, or other chemical compounds, these machines ensure consistent particle size and high-quality granulation. They cater to a wide range of production needs, from pilot-scale batches to large-scale manufacturing.

Every granulator goes through a stringent vetting process, ensuring quality and performance. Our machinery is cost-effective, promising significant savings compared to new equipment without compromising efficiency. Renowned brands like Glatt, Fette, and Diosna are part of our selection, known for their reliability and advanced technology. Prices range between €10,000 and €100,000, catering to diverse budget scales.

For detailed information or to request a quote, reach out to our dedicated team, ready to assist you with your specific needs. At Exapro, we're all about facilitating your business growth through quality and affordability. Trust in Exapro for your industrial machinery needs and boost your productivity today.

HOSOKAWA ALPINE AG ARC MS300 Pharmaceutical granulator

Year: 2020

Equipment: Roller compactor type: ARC MS300 Manufacturer: HOSOKAWA ALPINE AG (Germany) APPLICATION SECTIONS: Coal, chemical, food, fertilizer production year of manufacture: 2020 CONDITION: NEW (NOT USED) Units in stock: 1 LOCATION: NOVOKUZNETSK

VIANI MOD. EV 380 - Oscillating granulator used

Year: 2014

DESCRIPTION: Granulator mounted on a mobile stainless steel frame. The machine is particularly suitable for sieving granulates obtained eliminating lumps, making the granulate uniform to the desired size and, above all, avoiding crushing the product creating dust. Wide range of applications, various types of dry, wet and heat sensitive powders. SECTORS OF USE: Pharmaceutical, chemical, cosmetics, food, dietary, medical devices, …


MANES MOD. SE 300 - Oscillating granulator used

Year:

DESCRIPTION: Granulator mounted on a mobile stainless steel frame. The machine is particularly suitable for sieving granulates obtained eliminating lumps, making the granulate uniform to the desired size and, above all, avoiding crushing the product creating dust. Wide range of applications, various types of dry, wet and heat sensitive powders. SECTORS OF USE: Pharmaceutical, chemical, cosmetics, food, dietary, medical devices, …


Quadro Comil U10 granulator

Year: 2000

Speed (rpm) 3600 rpm
Motor Power 1.5 kW

Glatt WSG 60/100 Pharmaceutical granulator

Year: 1987

Capacity 280 kg/h
Motor Power 37 kW

Collette GRAL 25 Pharmaceutical granulator Low working hours

Year: 1996

Volume 17 L
Motor Power 3 kW
Speed (rpm) 2957 rpm

QUADRO COMIL 194 AS atex stainless steel screening granulator

Year: 1987

Capacity 1800 kg/h
Product type Solids
Speed (rpm) 1500 rpm
Motor Power 2 kW

JACKSON & CROCKATT MOD. NO.7 - Reciprocating granulator used

Year:

DESCRIPTION: Granulator mounted on a painted steel frame. SECTORS OF USE: Pharmaceutical, chemical, cosmetics, food, dietary, medical devices, manufacturing. MAIN FEATURES: The granulator offers the possibility of satisfying different granulometric needs simply by varying the sieve. Quick and easy cleaning without special mechanical tools. The machine is particularly suitable for sieving granulates eliminating lumps, standardizing the granulate to the desired …

DIOSNA P400 Pharmaceutical granulator

Year:

Volume 400 L
Motor Power 6 kW
Speed (rpm) 3000 rpm

Used Aeromatic PMA 600 Pharmaceutical granulator

Year: 1990

Capacity 280 kg/h
Speed (rpm) 3000 rpm
Volume 600 L
Motor Power 30 kW

Glatt GPCG3 Pharmaceutical granulator

Year: 1989

Capacity 5 kg/h
Speed (rpm) 3000 rpm
Volume 8.5 L

Zanchetta Rotolab - Granulator mixer

Year: 1998

Volume 2 L
Speed (rpm) 955 rpm

EIRICH R7 Pharmaceutical granulator

Year: 1983

Capacity 0 kg/h
Speed (rpm) 0 rpm
Motor Power 5.5 kW
Volume 50 L
Product type Solids

Frewitt MG 633 Pharmaceutical granulator

Year:

Capacity 1000 kg/h
Motor Power 1 kW
Speed (rpm) 2850 rpm

Collette (GEA) Gral 600 Pharmaceutical granulator

Year: 1983

Volume 600 L
Motor Power 37 kW
Speed (rpm) 135 rpm

DIOSNA P400-A Pharmaceutical granulator

Year:

Volume 400 L
Motor Power 32 kW
Speed (rpm) 3000 rpm

Rapid 8045 granulator

Year: 1997

Speed (rpm) 420 rpm
Motor Power 37 kW

Aeromatic Single spot SP65 Pharmaceutical granulator

Year: 1995

Volume 65 L
Motor Power 3000 kW
Speed (rpm) 400 rpm


Introduction to Granulators in the Pharmaceutical and Chemical Industries

Granulators are crucial equipment in the pharmaceutical and chemical industries, used to convert powders into granules, which are easier to handle, process, and utilize in various applications. Granulation enhances the flow properties, compressibility, and homogeneity of powders, making them suitable for tablet compression, capsule filling, and other dosage forms in pharmaceuticals. In the chemical industry, granulators are used to produce uniform granules for catalysts, fertilizers, detergents, and other chemical products.

Types of Granulators

There are several types of granulators used in the pharmaceutical and chemical industries, each with specific applications and advantages:

  1. Wet Granulators: These granulators use a liquid binder to agglomerate powder particles. The binder solution is sprayed onto the powder while mixing, forming wet granules that are then dried. This method is ideal for producing dense, strong granules.

  2. Dry Granulators: Also known as roller compaction or slugging, this method involves compacting powder into large, dense sheets or slugs, which are then milled into granules. Dry granulation is suitable for moisture-sensitive or heat-sensitive materials.

  3. High-Shear Granulators: These machines use a high-speed mixing blade and a chopper to mix powders and a binder solution, rapidly forming granules. High-shear granulators are known for their efficiency and are widely used in the pharmaceutical industry.

  4. Fluid Bed Granulators: In these granulators, the powder particles are fluidized in a stream of air, and a binder solution is sprayed from above, forming granules. Fluid bed granulation is ideal for uniform granule size and efficient drying.

  5. Oscillating Granulators: These machines use an oscillating rotor to mechanically process powder through a screen, forming granules. They are suitable for smaller production scales and provide good control over granule size.

  6. Continuous Granulators: Designed for high-volume production, these machines continuously process powders into granules, offering high efficiency and consistent product quality.

Key Features and Specifications

When selecting a granulator, several key features and specifications should be considered to ensure it meets production needs:

  • Granule Size Control: The ability to adjust the granule size is crucial for meeting specific product requirements.

  • Capacity: The throughput capacity of the granulator, measured in kg/h or tons/h, depending on the production scale.

  • Binder Compatibility: For wet granulators, compatibility with different types of binders and solvents is essential.

  • Temperature Control: Important for heat-sensitive materials, ensuring that the granulation process does not degrade the product.

  • Ease of Cleaning: Features that facilitate easy cleaning and maintenance, crucial for avoiding cross-contamination, especially in the pharmaceutical industry.

  • Automation and Control Systems: Advanced granulators may include automated process control, data logging, and integration with manufacturing execution systems (MES).

Advantages of Using Granulators

Investing in high-quality granulators offers numerous benefits:

  • Improved Product Uniformity: Granulation ensures uniform particle size and distribution, enhancing product quality.

  • Enhanced Flow Properties: Granules flow more easily than powders, improving the efficiency of downstream processes like tableting and encapsulation.

  • Better Compressibility: Granulated materials are more compressible, which is essential for forming tablets and other solid dosage forms.

  • Reduced Dust and Segregation: Granules generate less dust and are less prone to segregation, improving safety and consistency.

  • Versatility: Granulators can process a wide range of materials, making them suitable for various applications in pharmaceuticals and chemicals.

Considerations When Buying a Granulator

To select the right granulator for your needs, consider the following factors:

  • Material Characteristics: Understand the properties of the material to be granulated, including moisture content, sensitivity to heat, and required granule size.

  • Production Scale: Determine the volume of material to be processed to choose a granulator with suitable capacity.

  • Regulatory Compliance: Ensure the granulator meets industry-specific regulatory standards, such as GMP (Good Manufacturing Practice) for pharmaceuticals.

  • Ease of Cleaning and Maintenance: Consider machines with easy-to-clean designs to minimize downtime and avoid cross-contamination.

  • Budget: Balance the initial investment with long-term operational costs, including maintenance, consumables, and energy consumption.

  • Service and Support: Evaluate the availability of technical support and maintenance services for the machine.

  • Training: Assess the need for operator training to effectively use the machine’s advanced features.

Popular Brands and Pricing

Several reputable brands manufacture granulators known for their reliability and performance. Here are a few notable ones:

  • Frewitt: Known for high-precision granulators suitable for both the pharmaceutical and chemical industries. Prices typically range from $50,000 to $500,000, depending on the model and specifications.

  • Glatt: Offers a range of fluid bed and high-shear granulators, widely used in pharmaceutical manufacturing. Pricing generally ranges from $100,000 to $1 million.

  • Alexanderwerk: Specializes in dry granulation equipment, offering robust and efficient roller compactors. Prices generally fall between $60,000 and $400,000.

  • Fitzpatrick: Provides a variety of granulation equipment, including roller compactors and high-shear mixers. Prices typically range from $70,000 to $600,000.

  • GEA Group: Known for advanced granulation technology, including continuous granulators and high-shear mixers. Pricing generally ranges from $150,000 to over $1 million.

Conclusion

Granulators are essential in the pharmaceutical and chemical industries for transforming powders into manageable and processable granules. With various types such as wet, dry, high-shear, fluid bed, oscillating, and continuous granulators, selecting the right machine depends on specific production needs and material characteristics. Key factors to consider include granule size control, capacity, binder compatibility, temperature control, ease of cleaning, and automation. Leading brands like Frewitt, Glatt, Alexanderwerk, Fitzpatrick, and GEA Group offer a range of high-quality granulators to suit different applications and budgets. By carefully evaluating production volume, material properties, regulatory compliance, and budget, businesses can invest in the right granulator to enhance their manufacturing capabilities and ensure consistent, high-quality production.